Section 3.3: Adapting Knowledge to a Local Context
Margaret Harrison
Ian D. Graham
Beatrice Fevers
Why Should We Adapt Practice Guidelines for Local Use?
- Often there are many quality guidelines on the same topic, little need for a brand new guideline
 - Reduces duplication of effort and optimizes use of existing resources
 - Encourages consideration of implementation and 'fit' with the local context – enhances applicability
 - Typically engages end-users thus helping uptake
 
How Do We Adapt Practice Guidelines for Local Use?
- Using a transparent, rigorous and replicable process
 - Involves an explicit, participatory process involving relevant decision makers including clinicians, managers, researchers, and policy makers
 - Preserving the integrity of the evidence-based recommendations
 
What is the ADAPTE Process?
- The ADAPTE process consists of three main phases: 
- planning and set-up
 - adaptation, and
 - development of a final product
 
 - 9 modules
 - 24 Steps
 
Phase I: Set-Up
Preparation Module
Steps
- Establish an Organizing Committee and working panel, resource team
 - Select a topic using criteria
 - Check if adaptation is feasible
 - Identify necessary resources and skills
 - Complete tasks for set-up phase inc. terms of reference, declaration of conflicts of interest, consensus process, endorsement bodies, guideline authorship, dissemination and implementation strategies
 - Write the adaptation plan
 
Phase II: Adaptation
Scope and Purpose Module
- Determine/clarify health questions using PIPOH
 
Search and Screen Module
- Search for Guidelines and other relevant documentation
 - Screen retrieved guidelines – record characteristics/content
 - Reduce a large number of retrieved guidelines using AGREE instrument
 
Assessment Module
- Assess guideline quality
 - Assess guideline currency
 - Assess guideline content
 - Assess guideline consistency
 - Assess acceptability and applicability of recommendations
 
Decision and Selection Module
- Review Assessments
 - Select between guidelines and recommendations to create an adapted guideline
 
Customization Module
- Prepare draft adapted guideline
 
Phase III: Finalization
External Review and Acknowledgement Module
- External Review – target audience of the guideline
 - Consult with endorsement bodies
 - Consult with source guideline developers
 - Acknowledge source documents
 
Aftercare Planning Module
- Plan for aftercare of the adapted guideline
 
Final Production Module
- Produce final guideline document
 
Future Research
- Evaluation (effectiveness, efficiency) of the ADAPTE methodology by both guideline developers and those undertaking adaptation as 1st step in implementation
 - Development of tools to capitalize on implementation planning activity during guideline adaptation
 
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